On September 5, 2025, U.S. Senators Alex Padilla and Angela Alsobrooks, along with 21 others, filed a Resolution of Disapproval against Secretary of Health and Human Services Robert F. Kennedy, Jr. The resolution expresses a lack of confidence in Kennedy’s ability to fulfill his role, citing violations of laws and public trust due to his anti-science agenda. Specific concerns raised include his firing of the CDC director for resisting unscientific directives, the dissolution of health advisory panels, and the cancellation of research grants. Over 20 states and more than 1,000 HHS employees have called for his resignation. The resolution has garnered support from various health organizations and prominent Senate Democrats, with Padilla previously criticizing Kennedy’s qualifications and proposed changes to mental health services under HHS.